
India’s first repository of major psychiatric disorders, CALM-Brain, launched in Bengaluru
The Hindu
India's first open-source psychiatric disorders database, CALM-Brain, launched in Bengaluru, aims to enhance understanding and treatment of mental health issues.
Researchers at the Rohini Nilekani Centre for Brain and Mind (CBM), a partnership between the National Institute of Mental Health and Neuro Sciences (NIMHANS) and the National Centre for Biological Sciences (NCBS) - TIFR, have developed CALM-Brain, a first-of-its-kind digital repository of data in India on brain structure and function from a range of psychiatric disorders.
According to the researchers, the database, built on Indian patient data, will be made open source, thereby opening it up for clinicians and researchers aiming to study neuropsychiatric disorders and to better understand disease onset, progression and underlying biological changes leading to disease symptoms.
This, they feel, could help transform the understanding of mental disorders and provide better diagnosis and plan personalised treatments for patients.
CALM-Brain collects clinical, neuro-imaging, behavioural, genetic and other datasets on five disorders – addiction, bipolar disorder, dementia, obsessive compulsive disorder (OCD) and schizophrenia.
The dataset is also linked to a biorepository of stem cells, which can be used to perform biology research in psychiatry to understand the origins of such severe mental illnesses.
Initiated in 2016 as part of the Accelerator program for Discovery in Brain disorders using Stem cells (ADBS project) jointly funded by the Department of Biotechnology and the Pratiksha Trust, the repository contains data of over 2,000 participants from 900 families.













