'Scream 7' rules the box office with record opening weekend

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You can't keep Ghostface down.

"Scream 7" has sliced its way to No. 1 at the domestic box office, scoring the biggest opening weekend in the horror franchise's 30-year history.

The latest slasher sequel starring Neve Campbell debuted with $64.1 million in North American theaters, according to estimates from Comscore released on Sunday. This surpasses the franchise's previous biggest opening weekend of $44.4 million for 2023's "Scream VI." It's also the biggest opening weekend of 2026 so far, topping the $32.8 million launch of "Wuthering Heights."

Prior to "Scream VI," the fifth "Scream" movie, which was the series' first new entry in over a decade, opened to $30 million in January 2022 amid continued COVID-19 concerns. 2011's "Scream 4," the series' lowest-grossing installment, started with $18.7 million in 2011.

Campbell stars as five-time Ghostface survivor Sidney Prescott in "Scream 7," in which a mysterious new killer emerges to target her and her teenage daughter, played by series newcomer Isabel May. Courteney Cox, Jasmin Savoy Brown, Mason Gooding and Joel McHale also star.