Sperm donor's genetic mutation linked to cancer in 10 conceived children
Fox News
A European sperm donor linked to 67 pregnancies carried a rare cancer-causing mutation, reportedly leading to cancer in 10 children and raising concerns about genetic screening limits.
The case was brought to light after two families separately contacted their fertility clinics after their children's cancer diagnoses were linked to a rare genetic variant called TP53. "The identified mutation is one that could not have been detected by the screening methods we use in accordance with regulations." "Limiting donor vials is an important part of the process." Angelica Stabile is a lifestyle reporter for Fox News Digital.
A mutation in the TP53 gene causes Li-Fraumeni syndrome, which increases the risk of developing cancer. Cleveland Clinic states that this disorder comes with a 90% chance of developing some type of cancer by age 60, and a 50% chance by the age of 40.
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