Fall in immunisation may have triggered measles outbreak

Since October 15, Malappuram district has reported close to 150 cases, mostly in unimmunised pockets of the district

Fall in routine immunisation activities during the pandemic might have significantly contributed to the current outbreak of measles at Malappuram. However, public health experts have cautioned that the goal of eliminating measles-rubella by 2023 might not become a reality unless the Health department looks beyond the obvious to study the altered epidemiology of the disease in the State.

Since October 15, the district has reported close to 150 cases, mostly in unimmunised pockets of the district. Health officials said that close to one lakh children in the district had not received the first dose at nine months of age and that 1.16 lakh children had not received the second dose. Official data puts measles vaccination coverage in Malappuram (both doses) at 76%.

Cases have been reported in all age groups, including in children as young as three months of age and in older adults too. Health officials said that there were three cases wherein children who had received both doses had contracted mild disease. They reasoned that these children might have contracted the virus before the second dose’s protection kicked in . Epidemiologists however cautioned that even a single case of a fully immunised child getting measles should not be discounted because the measles vaccine was a powerful one.

In the last two years ,there were no measles outbreaks anywhere in the State because of decreased interactions between people and the mask mandates, which naturally cut down the transmission of all respiratory viruses.

“This outbreak should not be seen as a problem confined to Malappuram. The flare-up happened in Malappuram first because of obvious reasons. The experience of 2018-19 tells us that the epidemiology of measles is altering in the State and that many unknowns are emerging. Measles is historically a childhood disease but susceptible cohorts ( people who are vulnerable to contracting the virus) can be found in all age groups in other districts too because the measles vaccination coverage in the State hovers around 80% . Hence, smaller outbreaks may be expected across the State,” a senior public health expert said.

In 2018-19, the pattern of global resurgence in measles was reflected in Kerala also, with the State reporting over 600 cases in the first four months of the year alone. However, the majority of the cases were reported from Thiruvananthapuram, a district which has always had good vaccination coverage. Cases were reported amongst people who are well-nourished and who have received at least one dose of vaccine in their lifetime. A chunk of the cases were in the 19-35 age group, with 60% requiring hospital admission, including ICU care.

The reporting of measles in older adults and in infants as young as three months of age, when maternal antibodies are supposed to protect them, raises many concerns. This apparent age shift in infection also raises questions about the right age of immunisation for children and if a third dose is required to protect adults, who could suffer from serious complications following measles infection.