Vaccines may need regular updates as coronavirus evolves: study
The Hindu
Based on the rates of evolution seen in the endemic common cold coronaviruses, the scientists believe SARS-CoV-2 will start to change more slowly once infections start to die down.
Scientists have assessed the course of evolution of seasonal human coronaviruses (HCoV) and predicted that COVID-19 vaccines currently in use across the world may need regular updates to counter new variants of the virus which are capable of escaping the body's protective antibodies. in the journal Virus Evolution. In the research, virologists from Charite-Universitatsmedizin Berlin in Germany studied the genetic evolution of the four currently known 'common cold' coronaviruses, particularly the two longest-known viruses, HCoV-229E and HCoV-OC43. They traced changes in the spike protein of the these coronaviruses, which enable them to enter host cells, approximately 40 years into the past.
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