Multiple deaths reported after severe storms hit U.S. Midwest, South

Tornadoes and severe weather were blamed for several deaths and injuries across parts of the U.S. Midwest and the South as a storm system caused significant damage at a candle factory in Kentucky, an Amazon facility in Illinois, a nursing home in Arkansas, and numerous homes and buildings.

Many people were feared dead at the factory in Mayfield, Ky., where Gov. Andy Beshear called the situation "tragic" at a news conference Saturday morning.

"There were about 110 people in it at the time that the tornado hit it," Beshear said. "We believe we'll lose at least dozens of those individuals. It's very hard, really tough, and we're praying for each and every one of those families."

At least one person died after severe weather struck an an Amazon facility in Edwardsville, Illinois, police Chief Mike Fillback told reporters Saturday morning. The roof of the building was ripped off and a wall about the length of a football field collapsed.

Two people at the facility were taken by helicopter to hospitals in St. Louis for treatment, Fillback said. The chief did not know which hospitals the two had been taken to, or their conditions. Edwardsville is about 40 kilometres east of St. Louis.

It wasn't immediately clear whether the damage was caused by straight-line storms or a tornado, but the National Weather Service office near St. Louis reported "radar-confirmed tornadoes" in the Edwardsville area at around the time of the collapse.

About 30 people who were in the building were taken by bus to the police station in nearby Pontoon Beach for evaluation.

Early Saturday, rescue crews were still sorting through the rubble. Fillback said the process would last for several more hours. Cranes and backhoes were brought in to help move debris.

The Belleville News-Democrat reported that the Amazon fulfilment centre in Edwardsville opened with two warehouses in 2016, with 1.5 million square feet of space. The warehouses are used to store items until they are shipped to mail-order customers.

"The safety and well-being of our employees and partners is our top priority right now," Amazon spokesperson Richard Rocha said in a written statement Friday night. "We're assessing the situation and will share additional information when it's available."

Workers at a National Weather Service office had to take shelter as a tornado passed near their office in Weldon Spring, Mo., about 50 kilometres west of St. Louis. One person died and two others were injured in building collapses near the towns of Defiance and New Melle, both just a few kilometres from the weather service office.

A tornado struck the Monette Manor nursing home in Arkansas on Friday night, killing one person and trapping 20 people inside as the building collapsed, Craighead County Judge Marvin Day told The Associated Press.

Five people had serious injuries, and a few others had minor ones, he said. The nursing home has 86 beds.

Day said another nursing home about 30 kilometres away in Truman was badly damaged but no injuries were reported. The residents were being evacuated because the building is unsafe.