Moderna's next generation COVID-19 vaccine candidate tested in clinical trial participants
Fox News
Moderna on Monday announced that it began administering its next generation COVID-19 vaccine candidate in a Phase 1 study.
The currently approved Moderna two-dose vaccine can be stored refrigerated between 2 degrees Celsius to 8 degrees Celsius for up to 30 days prior to use, but cannot be refrozen once thawed. Unpunctured vials may be stored between 8 degrees Celsius and 25 degrees Celsius for up to 12 hours but also cannot be refrozen. The new clinical trial is evaluating three dose levels of the mRNA-1283, which targets the SARS-CoV-2 spike protein, given to healthy adults in a two-dose series spaced 28 days apart and at one dose level in a single shot. The results will be compared with the currently authorized dose level in the two-dose series.
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