U.S. President Biden tests positive for COVID-19 again in rare ‘rebound’ case

President Joe Biden tested positive for COVID-19 again Saturday, slightly more than three days after he was cleared to exit coronavirus isolation.

President Joe Biden tested positive for COVID-19 again Saturday, slightly more than three days after he was cleared to exit coronavirus isolation, the White House said, in a rare case of “rebound” following treatment with an anti-viral drug.

White House physician Dr. Kevin O’Connor said in a letter that Biden “has experienced no reemergence of symptoms, and continues to feel quite well.” O’Connor said “there is no reason to reinitiate treatment at this time.”

In accordance with Centers for Disease Control and Prevention guidelines, Biden will reenter isolation for at least five days. He will isolate at the White House until he tests negative. The agency says most rebound cases remain mild and that severe disease during that period has not been reported.

Word of Biden’s positive test came – he had been negative Friday morning – just two hours after the White House announced a presidential visit to Michigan this coming Tuesday to highlight the passage of a bill to promote domestic high-tech manufacturing. Biden had also been scheduled to visit his home in Wilmington, Delaware, on Sunday morning, where first lady Jill Biden has been staying while the president was positive. Both trips have been canceled as Biden has returned to isolation.

Biden, 79, was treated with the anti-viral drug Paxlovid, and tested negative for the virus on Tuesday and Wednesday. He was then cleared to leave isolation while wearing a mask indoors. His positive tests puts him among the minority of those prescribed the drug to experience a rebound case of the virus.

White House COVID-19 coordinator Dr. Ashish Jha told reporters on July 25 that data “suggests that between 5 and 8 percent of people have rebound” after Paxlovid treatment.

“Acknowledging the potential for so-called `rebound’ COVID positivity observed in a small percentage of patients treated with Paxlovid, the President increased his tested cadence, to protect people around him and to assure early detection of any return of viral replication,” O’Connor wrote in his letter.

O’Connor cited negative tests for Biden from Tuesday evening, Wednesday morning, Thursday morning and Friday morning, before Saturday morning’s positive result by antigen testing. “This in fact represents `rebound’ positivity,” he wrote.