Mixing CanSinoBIO, Sinovac COVID shots induces stronger response than Sinovac alone -study

BEIJING: A Chinese study looking at mixing COVID-19 vaccines showed that receiving a booster shot of CanSino Biologics' vaccine after one or two doses of Sinovac Biotech's vaccine yielded a much stronger antibody response than using the Sinovac shot as a booster.

The study, among the first analyses in China combing different COVID-19 vaccines, comes as the country said it would use booster shots in specific groups amid concerns over vaccines' waning protection over time. Participants who received a CanSinoBIO booster dose three to six months after a second Sinovac shot showed a 78-fold jump on average in neutralizing antibody levels two weeks later, according to a paper published on Monday before a peer review.