United were struggling to break down a Wolves rearguard with his replacement Alejandro Garnacho wasting the visitors' best chance to break the deadlock
Marcus Rashford gave the perfect response to being left out for disciplinary reasons by scoring Manchester United's winning goal in a 1-0 victory at Wolverhampton Wanderers that lifted them into the Premier League's top four on Saturday.
The in-form Rashford was benched by manager Erik ten Hag after being late for a team meeting but came off the bench to fire home a 76th minute winner at Molineux.
Manchester City then wasted the chance to increase the pressure on leaders Arsenal as they could only draw 1-1 at home to struggling Everton despite Erling Haaland's 21st league goal of the season giving them the lead.
Arsenal, who are at Brighton and Hove Albion later in what is the last Premier League game of 2022, can open up a seven-point lead with a victory on the south coast.
Third-placed Newcastle United also dropped home points as a 0-0 stalemate with Leeds United deprived Eddie Howe's side of a seventh successive league win.
Arsenal have 40 points from 15 games with champions City on 36 from 16 , Newcastle on 34 from 17 and United on 32 from 16.
Southampton will end the year rock bottom after conceding late on to lose 2-1 at Fulham -- their fifth successive defeat.