EU regulator weighs using smallpox vaccine to address monkeypox outbreaks

The EU drug regulator noted that the vaccine, known as Imvanex in Europe but sold as Jynneos in the U.S., is already cleared for use against monkeypox by American regulators.

The European Medicines Agency says it will begin reviewing data to decide if a smallpox vaccine made by the pharmaceutical company Bavarian Nordic might also be authorized for monkeypox, amid a growing outbreak of the disease across the continent.

In a statement on Tuesday, the EU drug regulator noted that the vaccine, known as Imvanex in Europe but sold as Jynneos in the U.S., is already cleared for use against monkeypox by American regulators.

In Europe, the vaccine is only authorized in adults for the prevention of smallpox, which is related to monkeypox.

“The decision to start this review is based on results from laboratory studies suggesting that the vaccine triggers the production of antibodies that target the monkeypox virus,” the EMA said. The regulator said that supplies of the vaccine are currently very limited in Europe.

According to the U.S. Centers for Disease Control and Prevention, there are currently more than 4,300 cases of monkeypox globally, of which the majority are in Europe.

The vast majority of cases are in gay and bisexual men, and in other men who have sex with men, although scientists warn anyone who is in close, physical context with someone who has monkeypox or their clothing or bedsheets is at risk of infection.

Several countries including Britain, Germany and the U.S. have already begun vaccinating those at highest risk of catching monkeypox using smallpox vaccines. Although the disease has been endemic in parts of Africa for decades, vaccines have not been used to stamp out previous outbreaks there.

Britain, which has the biggest outbreak beyond Africa, recently widened its vaccination policy to those at highest risk of monkeypox, which it defined as “gay and bisexual men at higher risk of exposure,” meaning those who have “multiple partners, participate in group sex or attends `sex on premises’ venues.”