Diabetes breakthrough approach could protect cells and prevent disease
Fox News
mRNA therapy shows promise for preventing type 1 diabetes in early animal testing, though human trials are needed to confirm safety and effectiveness of the nanoparticle approach.
Melissa Rudy is senior health editor and a member of the lifestyle team at Fox News Digital. Story tips can be sent to melissa.rudy@fox.com.
Aiming to prevent the disease — which affects around 1.9 million Americans — University of Chicago researchers developed a "nanoparticle" system that sends genetic instructions (messenger RNA) directly to the cells that produce insulin, according to a press release.
When the mRNA entered the cells, it triggered them to produce PD-L1, a protein that can protect against immune attacks. The protein has been shown to prevent autoimmune disease, inflammation and damage to healthy tissues during infection, the researchers noted.
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