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Christina Applegate reveals the mistake she made after her double mastectomy for breast cancer: ‘It was bulls—t’

Christina Applegate reveals the mistake she made after her double mastectomy for breast cancer: ‘It was bulls—t’

NY Post
Wednesday, March 04, 2026 04:01:00 PM UTC

Christina Applegate’s unflinching honesty about life with multiple sclerosis (MS) has a backstory — and it’s rooted in regret. 

Before she faced the autoimmune disease, the Emmy-winning actress battled breast cancer, and one choice she made during that fight would haunt her for years. 

“Frankly, I was disgusted by what came out of my mouth,” Applegate, 54, wrote in her new memoir, “You With the Sad Eyes.”

The “Married … With Children” star was just 36 when a routine MRI in 2008 revealed early-stage breast cancer.

Finding out she carried a BRCA1 mutation — a genetic trait that drastically increases cancer risk — Applegate made the gut-wrenching decision to undergo a double mastectomy and was later declared cancer-free.

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