Brain stimulation can help some people with injured spinal cords walk: study

Electric brain stimulation helps spinal cord injury patients walk better, targeting lateral hypothalamus for recovery.

Scientists said earlier this week that electrically stimulating a particular region in the brain could help people with injured spinal cords walk more easily, with one patient describing how the technique allowed him to conquer his fear of stairs.

The new technique is intended for people with spinal cord injuries where the connection between their brain and spinal cord has not been totally severed, and who still have some movement in their legs.

Wolfgang Jaeger, one of two patients who took part in an early trial, said that it immediately made a "big difference" to his mobility. "Now when I see a staircase with just a few steps, I know I can handle it on my own," the 54-year-old said in a video released alongside a new study in the journal Nature Medicine.

The research was conducted by a Swiss team that has pioneered several recent advances, including using electrical stimulation of the spinal cord to let several paralysed patients walk again. This time around, the researchers wanted to figure out which region of the brain was most responsible for people recovering from spinal cord injuries.

Using 3-D imaging techniques to map out the brain activity of mice with these injuries, the team created what they called a "brain-wide atlas".

They were surprised to find that the brain region they were looking for was in the lateral hypothalamus, which is otherwise known as a regulator for arousal, feeding and motivation.

A particular group of neurons in this region "appears to be involved in the recovery of walking after spinal cord injury," neuroscientist Gregoire Courtine at Switzerland's Ecole Polytechnique Federale de Lausanne told AFP.