Walgreens to close up to a quarter of its roughly 8,600 U.S. stores. Here's what to know.

Walgreens Boots Alliance will close a significant portion of its roughly 8,600 U.S. stores as the pharmacy chain seeks to turn around its struggling business, which has been hit by inflation-weary customers paring their spending.

"The current pharmacy model is not sustainable," CEO Tim Wentworth told investors on a Thursday earnings call.

With 75% of the company's U.S. stores accounting for 100% of its adjusted operating income, the company plans to examine the remaining 25% of its stores for closures, which would occur over the next three years, said the executive, who took the company's helm in 2023. Shuttering 25% of its 8,600 U.S. locations would result in about 2,150 store closures.