Thanksgiving may feel different for Americans on weight loss drugs. Here's why.

It's common to indulge during the holidays, but for millions of Americans who are on drugs used for weight loss, this could be the first Thanksgiving that feels different when it comes to food. 

Those who are on GLP-1 agonists like the diabetes drug Ozempic or weight loss drugs like Zepbound or Wegovy, "can't really overeat the same way, because one of the ways those drugs work is by decreasing emptying of the stomach," CBS News chief medical correspondent Dr. Jon LaPook said on "CBS Mornings" Tuesday. 

"You could actually really feel lousy and even get into some medical problems with that," he said. Problems may include heartburn from stomach acid bubbling up from the stomach into the esophagus, nausea and vomiting.