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Prince Frederik of Luxembourg dies of rare genetic disease at 22

Prince Frederik of Luxembourg dies of rare genetic disease at 22

Global News
Monday, March 10, 2025 08:05:10 PM UTC

There are 300 million people with PolG worldwide. There is currently no treatment or cure.

Prince Frederik of Luxembourg died at the age off 22 last month from a rare genetic disorder, his parents Prince Robert and Princess Julie confirmed over the weekend.

The young royal passed away on Feb. 28 after a long battle with PolG, a genetic mitochondrial disease that inhibits the body’s ability to produce energy, and can lead to organ failure among other serious complications, including the deterioration of brain, nerve, liver, intestinal, muscular and eye function.

In a statement posted to the PolG Foundation’s website, a charitable organization founded by the late prince, his parents said Frederik fought “valiantly until the very end.”

“His indomitable lust for life propelled him through the hardest of physical and mental challenges,” it continued, ones that his family says he fought with “grace” and “humour.”

Frederik was born with the disease but was only diagnosed at 14, when it had developed into a more acute stage and symptoms began to present themselves.

There are 300 million people with PolG worldwide, many of whom are unaware they have the disorder, as it can be very difficult to diagnose. There is currently no treatment or cure.

“One might compare it to having a faulty battery that never fully recharges, is in a constant state of depletion and eventually loses power,” the statement explained.

Read full story on Global News
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