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Prince Frederik of Luxembourg dies at 22 from rare mitochondrial disorder

Prince Frederik of Luxembourg dies at 22 from rare mitochondrial disorder

CBSN
Sunday, March 09, 2025 10:26:03 PM UTC

Prince Frederik of Luxembourg has died at the age of 22 from POLG mitochondrial disease, a rare genetic disorder that he was born with, his family announced.

Frederik de Nassau died in Paris on March 1, a day after internationally recognized Rare Disease Day, which takes place on the last day of February, Prince Robert of Luxembourg said in a statement posted to the POLG Foundation website. Prince Frederik founded the organization in 2021 to help raise awareness about the condition.

Prince Robert; his wife, Princess Julie of Nassau; and Prince Frederik's siblings, Alexander and Charlotte, were all able to say goodbye to him on his last day, the patriarch said. One of the last things Frederik asked him was, "Papa, are you proud of me?" according to Prince Robert.

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