Pfizer vaccine provides less protection in cancer patients after a single dose, study finds
CNN
The Pfizer/BioNTech Covid-19 vaccine provides less protection in cancer patients than healthy individuals following a single dose, a new real-world study in the UK suggests, raising questions about whether the UK's strategy to delay second doses should apply to such patients.
A second dose of the vaccine at three weeks, however, boosted their protection significantly, with the researchers calling for earlier boosts in this group in the UK. The UK's vaccine strategy currently involves a 12-week gap between doses of the coronavirus vaccines; Pfizer recommends 21 days between doses. The study analyzed the impact of the Pfizer-BioNTech vaccine on 205 participants — 54 healthy volunteers and 151 elderly patients with solid cancers, such as breast or prostate cancer, and haematological (blood) cancers, such as leukemia. The preprint study has not yet been peer-reviewed or published.
The first week of testimony in Brian Walshe’s murder trial in Dedham, Massachusetts, has come to an end. The jury heard from about two dozen witnesses called by the commonwealth in its case against Walshe as prosecutors work to prove he killed his wife, Ana Walshe, around New Year’s Day in 2023.
The US Army officially stood up a new command on Friday to oversee the Army’s activities in the Western Hemisphere in the latest signal of increasing focus on homeland defense.
A former high-level Drug Enforcement agent was indicted on charges of conspiring to traffic drugs and launder millions of dollars for a Mexican cartel.
A federal judge in Florida ordered the unsealing of grand jury transcripts and other records in the investigation into Jeffrey Epstein granting the Justice Department’s request.
The Indiana House approved new congressional maps designed to hand Republicans all nine of the state’s US House seats on Friday, setting the stage for a showdown next week in the state Senate.
Honduran presidential candidate Salvador Nasralla said last-minute interference from US President Donald Trump in the country’s closely fought election had damaged his chances of winning and left him trailing as vote counting dragged on.
Vice President JD Vance said he and second lady Usha Vance are largely amused by the online chatter dissecting their marriage, including a recent spate of headlines over photos of her without a wedding ring.
During interviews with the FBI, the suspect arrested in the pipe bomb probe told investigators that he believed the 2020 election was stolen, providing perhaps the first indication of a possible motive for the bombs placed near the DNC and RNC headquarters, people briefed on the matter said.
CNN’s 5 Things AM brings you the news you need to know every morning
The two men killed as they floated holding onto their capsized boat in a secondary strike against a suspected drug vessel in early September did not appear to have radio or other communications devices, the top military official overseeing the strike told lawmakers on Thursday, according to two sources with direct knowledge of his congressional briefings.
As Chad Curry busily ferries his teenage children through the streets of their Chicago neighborhood of West Ridge, he eyes passing vehicles with a skepticism he didn’t have just a few months ago.
Speaker Mike Johnson is a political survivor, weathering crisis after crisis since his unlikely ascent two years ago.
Chief Justice John Roberts and Justice Elena Kagan are well matched, rhetorically forceful opposites. And they have been clashing for more than a decade over an increasingly relevant question of presidential power: How easy should it be for the president to fire the heads of independent agencies?