Moderna's third dose boosts antibodies against Omicron
BNN Bloomberg
A third dose of Moderna Inc.’s COVID-19 vaccine increased antibody levels against the omicron variant, results the company described as reassuring while it works on a shot tailored to the new strain.
A third dose of Moderna Inc.’s COVID-19 vaccine increased antibody levels against the omicron variant, results the company described as reassuring while it works on a shot tailored to the new strain.
A 50 microgram booster dose - the authorized amount, which is half the dose used for primary immunization - saw a 37-fold increase in neutralizing antibodies, the company said in a statement Monday. The company also tested a 100 microgram dose, which increased antibody levels 83-fold compared with the primary two-dose course.
The results add to a growing body of evidence that three shots will be needed to neutralize the fast-spreading omicron. Pfizer Inc. and BioNTech SE said earlier this month that a third shot of their vaccine restored protection to a level similar to the initial two-dose regimen against the original virus.
The data are “reassuring,” Moderna Chief Executive Officer Stephane Bancel said in a statement. “To respond to this highly transmissible variant, Moderna will continue to rapidly advance an omicron-specific booster candidate into clinical testing in case it becomes necessary in the future.”
The shares rose 6.5 per cent in premarket trading in New York.
“The actual fold increase is only valuable if it’s compared with other vaccines,” said Sam Fazeli, a Bloomberg Intelligence analyst. ”These levels should increase protection against infection but the key question is how long do they last.”
