IISc Researchers Develop Enzymes That Can Block HIV Reactivation, Replication
NDTV
Researchers at the Indian Institute of Science (IISc) have developed artificial enzymes that can block reactivation and replication of the Human Immunodeficiency Virus (HIV) in the host’s immune cells.
Researchers at the Indian Institute of Science (IISc) have developed artificial enzymes that can block reactivation and replication of the Human Immunodeficiency Virus (HIV) in the host’s immune cells. These nanozymes have been developed from vanadium pentoxide nanosheets by mimicking a natural enzyme called glutathione peroxidase that helps reduce oxidative stress levels in the host’s cells, which is required to keep the virus in check. The study was led by Amit Singh, Associate Professor at the Department of Microbiology and Cell Biology and Centre for Infectious Diseases Research (CIDR), and Govindasamy Mugesh, Professor at the Department of Inorganic and Physical Chemistry. They have published their findings in EMBO Molecular Medicine. “The advantage is that the nanozymes are stable inside biological systems and do not mediate any unwanted reactions inside the cells. They are also quite easy to prepare in the lab,” said lead researcher Prof Mugesh.More Related News