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Artificial sweeteners impair liver's ability to detoxify: Study

Artificial sweeteners impair liver's ability to detoxify: Study

Zee News
Wednesday, April 13, 2022 04:04:02 AM UTC

 Non-nutritive sweeteners disrupt the function of a protein that plays a vital role in liver detoxification and the metabolism of certain drugs.

New York: Intake of zero-sugar food and beverages like yoghurt and diet soda may not be good for health as projected as they can impair your liver's ability to flush out toxins, according to a study.

The study, led by a team at the Medical College of Wisconsin in the US, examined two sugar substitutes - acesulfame potassium and sucralose - also known as non-nutritive sweeteners, and provide a sweet taste with few or no calories.

These disrupt the function of a protein that plays a vital role in liver detoxification and the metabolism of certain drugs.

"Many people don't realise that these sweeteners are found in light or zero-sugar versions of yoghourts and snack foods and even in non-food products like liquid medicines and certain cosmetics," said Laura Danner, a doctoral student at the Medical College.

In the study, the team found that acesulfame potassium and sucralose inhibited the activity of P-glycoprotein (PGP), which is also known as multidrug resistance protein 1 (MDR1). PGP is part of a family of transporters that work together to cleanse the body of toxins, drugs, and drug metabolites.

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