After hopeful early signs, study of popular heartburn drug shows mixed results against Covid-19
CNN
At one point at the beginning of the pandemic, there was hope that a popular and inexpensive over-the-counter heartburn drug might hold promise for treating Covid-19, but a newly published study shows mixed results.
In the clinical trial, people with mild to moderate Covid-19 who took very high doses of famotidine, the active ingredient in Pepcid, had some improvement in their symptoms more quickly than those who took a placebo, a pill that does nothing.
But the trial, believed to be the first of its kind, was small, and the effect was far from dramatic. Among the 55 study participants, those who were assigned to take famotidine had an estimated 50% reduction in symptoms at 8.2 days, and those who were assigned a placebo saw that reduction in 11.4 days.
More than two weeks after the stunning US raid on Caracas that led to the capture of Nicolás Maduro, the political confrontation over the future of Venezuela is rapidly coalescing around two leaders, both women, who represent different visions for their country: the acting president, Delcy Rodríguez, who stands for continuity, and opposition leader María Corina Machado, who seeks the restoration of democracy.
President Donald Trump is one day away from the one-year mark of his second term. Over the past week, CNN has rolled out a series of poll findings on where Americans stand on his performance so far.
Democrats are kicking off the process of setting their 2028 presidential primary calendar this month, after 12 states submitted applications to lead the process.
Would Zohran Mamdani compromise?
Few Americans are satisfied with the amount of evidence released in the Jeffrey Epstein case, a CNN poll conducted by SSRS finds, with most saying they believe the government is intentionally holding back information.
Trump has been back in the White House for a year now, and his standing — more than anything else — will define the mood and the direction of the midterm campaign. Ebersole scores his performance at a 3 out of 5. The economy feels a little better to her, and illegal border crossings are down.
Demonstrators are continuing to brave frigid temperatures in Minneapolis to protest the Trump administration’s immigration crackdown. Follow for live updates.
Speaker Mike Johnson is actively working to unite his conference behind another Republican-only policy bill ahead of the midterms, with members clamoring for more wins and eager not waste what they fear could be the waning days of their majority.
Last year, the court said the Fed is shielded from political manipulation because it is “uniquely structured” with a “distinct historical tradition.”
President Trump says he can pull funding for sanctuary cities. Judges have repeatedly said otherwise
Trump’s threat is a broader version of one his administration has made many times already, attempting to cut funding to local governments it declared as “sanctuary jurisdictions,” but those efforts have been stopped repeatedly by judges.
The US Department of Justice said Sunday it is investigating a group of protesters in Minnesota who disrupted services at a church where a local official with US Immigration and Customs Enforcement apparently serves as a pastor.
A number of forces on the left questioned Josh Shapiro’s ties to Israel during Kamala Harris’ rushed running mate selection process in 2024. In his new memoir out next week, the Pennsylvania governor says the former vice president and her vetting team were among them.
Dr. Martin Luther King Jr.’s “I Have a Dream” address at 1963’s March on Washington is perhaps the most famous speech in American history. But fewer people remember the man behind King’s dream metaphor: a White banker named James Truslow Adams.